Born in São Paulo and Bachelor in Music by UNESP, Manuela Freua's debut was as First Witch in Purcell's Dido and Aeneas. Since then, she has been seen as a soloist in productions of Violanta (Korngold), Der Schauspieldirektor (Mozart), Il Matrimonio Segreto (Cimarosa), Gianni Schicchi (Puccini), Pélleas et Melisande (Debussy), Les Troyens (Berlioz), Yerma (Villa-Lobos), Roméo et Juliette (Gounod), Lo Schiavo (Gomes), Die Lustige Witwe (Lehár), Les Pecheurs de Perles (Bizet), La Bohème (Puccini), Hänsel und Gretel (Humperdinck), Pagliacci (Leoncavallo) among others, in stages such as São Paulo’s Theatro Municipal, Theatro São Pedro, Sala São Paulo and Teatro Amazonas.
She is part of Ópera Curta Company, as Violetta in La Traviata. Intensively active as a chamber music singer, she has performed in concerts such as Lied (CCBB - São Paulo), XX Century Music Cycle, Voices of Villa and Debussy l'après-midi avec Mallarmé, having sung in concerts in Hungary and Japan. She has sung the soprano parts of Beethoven’s 9th Symphony, with OSPA and Mahler’s 8th Symphony (OSESP). Manuela has received prizes in all of Brazil's most important singing competitions. She was also seen in the Brazilian production of the musical "Les Misérables", and in the Collegium Musicum de São Paulo Choir, directed by Abel Rocha.